Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

朱尔斯皮耶里
AT&T (T, Fortune 500) approved a stock repurchase of up to 300 million shares worth about $10.5 billion in March. The buyback is the fourth initiative announced over the past three years. Since 2012, when the company started its stock buybacks, it has repurchased 775 million of its shares.
其实我一直都在等你提到篮网队的处境,既然你没说,那就我来说吧。林书豪已经因腿筋受伤缺阵几周了。他们是唯一有摆烂权利但是不摆烂的球队!
Best chances: It's always hard to bet against Streep getting a best actress nomination, and Hanks is overdue for an acting nomination after missing out in recent years.
Warren Buffett reclaimed the No. 2 spot on the list for the first time since 2014, with a net worth of $75.6 billion, up from $60.8 billion in 2016.
A number of nude photographs have been leaked online after several female students offered the photos in exchange for high-interest loans via an online lending platform.
价格:197.5万美元(约合人民币1226万元)
今年上榜的十亿美元级富豪为1810名,低于去年1826人的记录。上榜富豪净资产总计为64800亿美元,比去年减少了5700亿美元。
Over the next few years, large residential buildings will have to comply with Local Law 87, which requires them to audit energy usage and keep systems running at peak efficiency. Residential buildings are the city’s largest source of greenhouse gas emissions, accounting for 37 percent of the total. “The one hot-button topic is energy. How do buildings become more energy efficient?” said Dan Wurtzel, the president of FirstService Residential New York, which manages more than 500 properties. “If a third of your operating budget is related to energy and you can now reduce that cost, you can take pressure off the need for a maintenance increase.”
Former Disney star-turned-wild child singer Miley Cyrus followed as the number two 'celeb gone good', according to the website. Father-to-be Channing Tatum came in third.
HOUSE OF CARDS (Netflix, Feb. 27) Netflix’s political grand guignol gets a 13-episode third season. Kim Dickens of “Treme” joins Kevin Spacey and Robin Wright in the cast, and two members of Pussy Riot will make a guest appearance.
时间:2011-03-08 编辑:beck
['gl?ub?l]
对于其他队伍而言,在球场上拥有良好判断力的德国也是一直非常出色的队伍。意大利也是世界杯上无法忽视的队伍,而拥有罗纳尔多的葡萄牙队将会是一直极具危险性的队伍。拥有众多的大将的比利时队也将成为人们口中津津乐道的黑马队伍。
该研究的公布正值美国政界反中国言论日益增加之际,此外,今年夏天3起针对从中国进口的钢铁产品的政治敏感反倾销案件即将作出裁决,可能导致美方对中国企业施加高达500%的惩罚性关税。
9. Mila Kunis - $11 million
为了让故事更符合现代读者的口味,新作加入了一些“小花样”,包括吸烟会导致癌症的广告词以及一位跟邦德不相上下的女性。
It was apparent not just in obvious brand extensions, like Banana Republic’s “Mad Men” collection (designed in collaboration with the show’s costume supremo, Janie Bryant), but in more pervasive, unspoken ways: in silhouette and print; in hemline and seam. And in the clear belief, visible on catwalks everywhere, that the 1960s were the answer to every moment of pallid inspiration, or aesthetic doubt.
It is not yet known who will look after Choupette after Lagerfeld's death.
献上节日的问候与祝福,愿你拥有一个充满生机和欢乐的新年。
'People go crazy and it gets overwhelming.'
我们都将直上天堂,我们都将直下地狱
目前,中国15座城市允许对某些国家的公民实行72小时免签证入境。上海、江苏和浙江则为来自某些国家的国际过境旅客提供144小时免签证停留。
戛纳电影节素以质问与嘲笑著名。在本届电影节上,《青木原树海》(Sea of Trees)成为第一部遭遇观众挑剔的电影。该片由格斯?范?桑特Gus Van Sant指导。在媒体放映场,《青木原树海》遭遇嘲弄的风暴,陷入了嘘声之海。由于这些发生在首映红毯前,恶评迅速传播,使得盛典蒙上阴影。娜奥米?沃茨(Naomi Watts )和 马修?麦康纳(Matthew McConaughey)走上红毯时,《每日电讯报》(Daily Telegraph)形容此场景为“极其糟糕却又引人瞩目的羞辱之途”。但是在随后的新闻发布会上,马修?麦康纳,这位来自德克萨斯的演员表情坦然,“每个人都有权倒喝彩,正如他们有权喝彩一样,”他说道。我相信我们都知道他的意思。
At the center of the speculation is BlackBerry’s healthy intellectual property portfolio, 44,000 patents and still growing. Last October, for example, the company won at least 27 new ones—covering everything from conference-calling interfaces to touch screens to security features for wearable technologies such as smart watches, eyeglasses and fitness bands. Security continues to be BlackBerry’s biggest selling point with businesses. Just ask the Sony movie studio division, which “resorted” to outdated BlackBerrys to restart communications after its security breach last Thanksgiving.


Aspiring young leaders already place more emphasis on using their influence, rather than trying to exert power through the embedded authority of their position or their assigned title. Many are already gaining leadership experience, not through promotion at established institutions but by running bottom-up movements and voluntary groups, or by shaping their own start-ups.
Dachis says: Zynga struggled to maintain its momentum and diversify its business in 2012. The difficult year was evident in reduced brand discussion and an increase in negativity from product shutdowns that leave the game company with a lot of work to do in 2013.
据透露,二月份哈迪德眯着眼睛试图模仿佛像,冒犯了许多人,在那之后她的签证申请就被驳回了。


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

AIG CEO Robert Benmosche will be voted CEO of the Year.
《秦时丽人明月心》
The banks' ability to return money to shareholders have declined. The slowing earning growth, high nonperforming loans and required deposits on the reserve have placed pressure on the banks in regards to capital supplement, said Guo Tianyong, director of the China Banking Research Center at the Central University of Finance and Economics.
在甲骨文球场以77比111耻辱性地输掉的这场比赛中,科比11投仅1中,其中三分球7投1中,全场只拿下4分。在上个赛季输给圣安东尼奥马刺队的比赛中。他也曾14投1中。

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

In 2016, China's box-office experienced a shock correction, with growth plummeting to just 3.7 percent from a roaring 48 percent rate in 2015.

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

Indeed. That's an understated benefit of Philly tanking so hard in recent years: they are so bad it disincentives other clubs from tanking because they'll struggle to be as bad as the Sixers. The Mavericks are in the mix, at least.
另一方面,世界杯作为体育盛事和文化体验也成为了热门搜索项。

The North has already warned that Park will "pay for his crimes in blood" if copies of the film make it across the border.
Not because I am happy to see the end of what was one of television’s smartest series, a pioneer of what is now generally accepted as the current golden age of small-screen serials.
总的来说:世界最大经济体任然可以入常运转就如同沙漠中的绿洲就算有末世预言宣称那样的日子已经远去了。
My Dear Wife
《江南Style》击败《Call Me Maybe》成为最受热捧的流行歌曲,而《007:天降杀机》战胜了《普罗米修斯》成为最多人查询的电影。
The Wizards need to surge ASAP if they want to stay in this. We saw what happened last year when they waited too long to get it together.

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


杭州住房租赁监管服务平台 可在线提取公积金了


References

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2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


"That of course is in keeping with all of the developments that we have seen in China in recent years, including the current enormous emphasis on innovation as a major component in the transition of the Chinese economy from 'Made in China' to 'Created in China'," he said.
9.Be Honest
AR could be the bigger opportunity after Apple’s Tim Cook gave the technology his backing — it was included in Apple’s latest operating system and its iPhone X device.
根据花旗居屋(Citi Habitats)提供的数据,在布鲁克林拟于明年投放市场的6527套新出租屋中,有1442套分布在贝德福德-斯图文森(Bedford-Stuyvesant)、布什维克(Bushwick)和克林顿山(Clinton Hill)。就在不久前,这些社区都还被视为不热门的地区。
The booming Internet economy now is playing an increasingly important role in supporting wealth growth in China's IT industry.
虽然香港、悉尼和温哥华地处全球的不同角落,但是它们有着同一个特征。
如果你没听过这句话,你去年绝对没上过中文网。这句简单的话是留在魔兽BBS上的,不知道什么原因——有说法是有网络公司是幕后推手——这句话吸引了710万人点击,在发布后24小时内产生了30万条评论。
恭贺新年。
The University of Pittsburgh team used stem cells made from skin to make MCPs, a special kind of cell that acts as a precursor to cardiovascular tissue. They then placed these cells on a 3-D scaffold designed to support a mouse heart. Within 20 days, the new heart began beating at 40 to 50 beats per minute.
鉴于之前许多邦女郎在007电影中如昙花般一现,随后便星途黯淡,玛尔洛和经纪人正努力确保她与众多一流演员合作,正如邦德电影是用来为她的国际演艺生涯铺路一样。

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



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粮食指数下滑约3%。
If any movie can bridge the deep racial, generational and class divides in American life — at least for a couple of hours — it would have to be this revival of the ancient “Rocky” franchise. Sylvester Stallone, shuffling into the wise old trainer role, gives perhaps the loosest, warmest performance of his career. Michael B. Jordan, as Adonis Johnson, Rocky’s protégé (and the illegitimate son of his onetime rival and long-lost friend, Apollo Creed), continues his emergence as one of the vital movie stars of our moment. As for Mr. Coogler, with his second feature as a director he proves himself to be a true contender. (Read the review)
时间长度:24个月
If it isn't appropriate to interrupt, make a quick note of your question so you don't forget, and ask later.

['?:d?ri?]

  • Only the first three authors are listed, followed by "et al."
  • 李迅雷:目前房地产行业的最大压力是库存过大
  • 发改委为小区物业费松绑 高端住宅物业费将上涨


“I am so overwhelmed and elated that fur has been banned from London Fashion Week! Progress!” Faith wrote.
China has long since eclipsed Russia as the world's number two power behind the US.

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